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An antagonism between Spinophilin and Syd-1 operates upstream of memory-promoting presynaptic long-term plasticity

We still face fundamental gaps in understanding how molecular plastic changes of synapses intersect with circuit operation to define behavioral states. Here, we show that an antagonism between two conserved regulatory proteins, Spinophilin (Spn) and Syd-1, controls presynaptic long-term plasticity a...

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Detalles Bibliográficos
Autores principales: Ramesh, Niraja, Escher, Marc, Turrel, Oriane, Lützkendorf, Janine, Matkovic, Tanja, Liu, Fan, Sigrist, Stephan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588984/
https://www.ncbi.nlm.nih.gov/pubmed/37767892
http://dx.doi.org/10.7554/eLife.86084