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Permission to pass: on the role of p53 as a gatekeeper for aneuploidy
Aneuploidy—the karyotype state in which the number of chromosomes deviates from a multiple of the haploid chromosome set—is common in cancer, where it is thought to facilitate tumor initiation and progression. However, it is poorly tolerated in healthy cells: during development and tissue homeostasi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Netherlands
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589155/ https://www.ncbi.nlm.nih.gov/pubmed/37864038 http://dx.doi.org/10.1007/s10577-023-09741-9 |