Enhancing a Sphaerobacter thermophilus ω-transaminase for kinetic resolution of β- and γ-amino acids

Sphaerobacter thermophilus synthesizes an ω-transaminase (ω-TA) that allows the production of enantiomerically pure β-amino acids. To obtain ω-TA variants with a higher activity and more favorable properties for industrial use, we modified critical amino acid residues either in the catalytic center...

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Detalles Bibliográficos
Autores principales: Wegner, Uwe, Matthes, Falko, von Wirén, Nicolaus, Lemke, Ina, Bode, Rüdiger, Vorbrodt, H.-Matthias, Rauter, Marion, Kunze, Gotthard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589169/
https://www.ncbi.nlm.nih.gov/pubmed/37864072
http://dx.doi.org/10.1186/s13568-023-01623-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589169/
https://www.ncbi.nlm.nih.gov/pubmed/37864072
http://dx.doi.org/10.1186/s13568-023-01623-x

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