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Characterizing the profiles of patients with acute concussion versus prolonged post-concussion symptoms in Ontario

Identifying vulnerability factors for developing persisting concussion symptoms is imperative for determining which patients may require specialized treatment. Using cross-sectional questionnaire data from an Ontario-wide observational concussion study, we compared patients with acute concussion (≤ ...

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Autores principales: Scott, Olivia F. T., Bubna, Mikaela, Boyko, Emily, Hunt, Cindy, Kristman, Vicki L., Gargaro, Judith, Khodadadi, Mozhgan, Chandra, Tharshini, Kabir, Umme Saika, Kenrick-Rochon, Shannon, Cowle, Stephanie, Burke, Matthew J., Zabjek, Karl F., Dosaj, Anil, Mushtaque, Asma, Baker, Andrew J., Bayley, Mark T., Tartaglia, Maria Carmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589269/
https://www.ncbi.nlm.nih.gov/pubmed/37863954
http://dx.doi.org/10.1038/s41598-023-44095-6
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author Scott, Olivia F. T.
Bubna, Mikaela
Boyko, Emily
Hunt, Cindy
Kristman, Vicki L.
Gargaro, Judith
Khodadadi, Mozhgan
Chandra, Tharshini
Kabir, Umme Saika
Kenrick-Rochon, Shannon
Cowle, Stephanie
Burke, Matthew J.
Zabjek, Karl F.
Dosaj, Anil
Mushtaque, Asma
Baker, Andrew J.
Bayley, Mark T.
Tartaglia, Maria Carmela
author_facet Scott, Olivia F. T.
Bubna, Mikaela
Boyko, Emily
Hunt, Cindy
Kristman, Vicki L.
Gargaro, Judith
Khodadadi, Mozhgan
Chandra, Tharshini
Kabir, Umme Saika
Kenrick-Rochon, Shannon
Cowle, Stephanie
Burke, Matthew J.
Zabjek, Karl F.
Dosaj, Anil
Mushtaque, Asma
Baker, Andrew J.
Bayley, Mark T.
Tartaglia, Maria Carmela
author_sort Scott, Olivia F. T.
collection PubMed
description Identifying vulnerability factors for developing persisting concussion symptoms is imperative for determining which patients may require specialized treatment. Using cross-sectional questionnaire data from an Ontario-wide observational concussion study, we compared patients with acute concussion (≤ 14 days) and prolonged post-concussion symptoms (PPCS) (≥ 90 days) on four factors of interest: sex, history of mental health disorders, history of headaches/migraines, and past concussions. Differences in profile between the two groups were also explored. 110 patients with acute concussion and 96 patients with PPCS were included in our study. The groups did not differ on the four factors of interest. Interestingly, both groups had greater proportions of females (acute concussion: 61.1% F; PPCS: 66.3% F). Patient profiles, however, differed wherein patients with PPCS were significantly older, more symptomatic, more likely to have been injured in a transportation-related incident, and more likely to live outside a Metropolitan city. These novel risk factors for persisting concussion symptoms require replication and highlight the need to re-evaluate previously identified risk factors as more and more concussions occur in non-athletes and different risk factors may be at play.
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spelling pubmed-105892692023-10-22 Characterizing the profiles of patients with acute concussion versus prolonged post-concussion symptoms in Ontario Scott, Olivia F. T. Bubna, Mikaela Boyko, Emily Hunt, Cindy Kristman, Vicki L. Gargaro, Judith Khodadadi, Mozhgan Chandra, Tharshini Kabir, Umme Saika Kenrick-Rochon, Shannon Cowle, Stephanie Burke, Matthew J. Zabjek, Karl F. Dosaj, Anil Mushtaque, Asma Baker, Andrew J. Bayley, Mark T. Tartaglia, Maria Carmela Sci Rep Article Identifying vulnerability factors for developing persisting concussion symptoms is imperative for determining which patients may require specialized treatment. Using cross-sectional questionnaire data from an Ontario-wide observational concussion study, we compared patients with acute concussion (≤ 14 days) and prolonged post-concussion symptoms (PPCS) (≥ 90 days) on four factors of interest: sex, history of mental health disorders, history of headaches/migraines, and past concussions. Differences in profile between the two groups were also explored. 110 patients with acute concussion and 96 patients with PPCS were included in our study. The groups did not differ on the four factors of interest. Interestingly, both groups had greater proportions of females (acute concussion: 61.1% F; PPCS: 66.3% F). Patient profiles, however, differed wherein patients with PPCS were significantly older, more symptomatic, more likely to have been injured in a transportation-related incident, and more likely to live outside a Metropolitan city. These novel risk factors for persisting concussion symptoms require replication and highlight the need to re-evaluate previously identified risk factors as more and more concussions occur in non-athletes and different risk factors may be at play. Nature Publishing Group UK 2023-10-20 /pmc/articles/PMC10589269/ /pubmed/37863954 http://dx.doi.org/10.1038/s41598-023-44095-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Scott, Olivia F. T.
Bubna, Mikaela
Boyko, Emily
Hunt, Cindy
Kristman, Vicki L.
Gargaro, Judith
Khodadadi, Mozhgan
Chandra, Tharshini
Kabir, Umme Saika
Kenrick-Rochon, Shannon
Cowle, Stephanie
Burke, Matthew J.
Zabjek, Karl F.
Dosaj, Anil
Mushtaque, Asma
Baker, Andrew J.
Bayley, Mark T.
Tartaglia, Maria Carmela
Characterizing the profiles of patients with acute concussion versus prolonged post-concussion symptoms in Ontario
title Characterizing the profiles of patients with acute concussion versus prolonged post-concussion symptoms in Ontario
title_full Characterizing the profiles of patients with acute concussion versus prolonged post-concussion symptoms in Ontario
title_fullStr Characterizing the profiles of patients with acute concussion versus prolonged post-concussion symptoms in Ontario
title_full_unstemmed Characterizing the profiles of patients with acute concussion versus prolonged post-concussion symptoms in Ontario
title_short Characterizing the profiles of patients with acute concussion versus prolonged post-concussion symptoms in Ontario
title_sort characterizing the profiles of patients with acute concussion versus prolonged post-concussion symptoms in ontario
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589269/
https://www.ncbi.nlm.nih.gov/pubmed/37863954
http://dx.doi.org/10.1038/s41598-023-44095-6
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