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White targeted chromatographic screening method of Molnupiravir and its metabolite with degradation kinetics characterization and in-silico toxicity

SARS-CoV-2 virus triggered a worldwide crisis, with world nations putting up massive efforts to halt its spread. Molnupiravir (MLN) was the first oral, direct-acting antiviral drug approved for nasopharyngeal SARS-CoV-2 infection with favorable safety and tolerability profile. This study aims at det...

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Detalles Bibliográficos
Autores principales: Aboras, Sara I., Megahed, Ahmed A., El-Yazbi, Fawzy, Maher, Hadir M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589288/
https://www.ncbi.nlm.nih.gov/pubmed/37863912
http://dx.doi.org/10.1038/s41598-023-44756-6