Cargando…
Inflammatory cell death, PANoptosis, screen identifies host factors in coronavirus innate immune response as therapeutic targets
The COVID-19 pandemic, caused by the β-coronavirus (β-CoV) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to cause significant global morbidity and mortality. While vaccines have reduced the overall number of severe infections, there remains an incomplete understanding of vi...
Autores principales: | Malireddi, R. K. Subbarao, Bynigeri, Ratnakar R., Mall, Raghvendra, Connelly, Jon P., Pruett-Miller, Shondra M., Kanneganti, Thirumala-Devi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589293/ https://www.ncbi.nlm.nih.gov/pubmed/37864059 http://dx.doi.org/10.1038/s42003-023-05414-9 |
Ejemplares similares
-
Whole-genome CRISPR screen identifies RAVER1 as a key regulator of RIPK1-mediated inflammatory cell death, PANoptosis
por: Malireddi, R.K. Subbarao, et al.
Publicado: (2023) -
Pancancer transcriptomic profiling identifies key PANoptosis markers as therapeutic targets for oncology
por: Mall, Raghvendra, et al.
Publicado: (2022) -
ZBP1 Drives IAV-Induced NLRP3 Inflammasome Activation and Lytic Cell Death, PANoptosis, Independent of the Necroptosis Executioner MLKL
por: Malireddi, R. K. Subbarao, et al.
Publicado: (2023) -
PANoptosis components, regulation, and implications
por: Malireddi, R.K. Subbarao, et al.
Publicado: (2020) -
ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection
por: Karki, Rajendra, et al.
Publicado: (2022)