Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling

Toll-like receptors (TLRs) are a class of proteins that play critical roles in recognizing pathogens and initiating innate immune responses. TASL, a recently identified innate immune adaptor protein for endolysosomal TLR7/8/9 signaling, is recruited by the lysosomal proton-coupled amino-acid transpo...

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Detalles Bibliográficos
Autores principales: Chen, Xudong, Xie, Min, Zhang, Sensen, Monguió-Tortajada, Marta, Yin, Jian, Liu, Chang, Zhang, Youqi, Delacrétaz, Maeva, Song, Mingyue, Wang, Yixue, Dong, Lin, Ding, Qiang, Zhou, Boda, Tian, Xiaolin, Deng, Haiteng, Xu, Lina, Liu, Xiaohui, Yang, Zi, Chang, Qing, Na, Jie, Zeng, Wenwen, Superti-Furga, Giulio, Rebsamen, Manuele, Yang, Maojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589346/
https://www.ncbi.nlm.nih.gov/pubmed/37863913
http://dx.doi.org/10.1038/s41467-023-42210-9

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