Glucocorticoid receptor-NECAB1 axis can negatively regulate insulin secretion in pancreatic β-cells

The mechanisms of impaired glucose-induced insulin secretion from the pancreatic β-cells in obesity have not yet been completely elucidated. Here, we aimed to assess the effects of adipocyte-derived factors on the functioning of pancreatic β-cells. We prepared a conditioned medium using 3T3-L1 cell...

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Detalles Bibliográficos
Autores principales: Udagawa, Haruhide, Funahashi, Nobuaki, Nishimura, Wataru, Uebanso, Takashi, Kawaguchi, Miho, Asahi, Riku, Nakajima, Shigeru, Nammo, Takao, Hiramoto, Masaki, Yasuda, Kazuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589354/
https://www.ncbi.nlm.nih.gov/pubmed/37863964
http://dx.doi.org/10.1038/s41598-023-44324-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589354/
https://www.ncbi.nlm.nih.gov/pubmed/37863964
http://dx.doi.org/10.1038/s41598-023-44324-y

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