Severe Aortic Valvular Incompetence From IgG4-Related Disease: An Unusual Entity

IgG4-related disease (IgG4-RD) is a new clinical entity characterized by lymphoplasmacytic lesions rich in IgG4-positive plasma cells. Myocardial involvement is extremely rare and not a typical cardiovascular manifestation of IgG4-RD. We report a rare case of IgG4-RD–associated myocardial mass causi...

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Autores principales: Soh, Bing Wei Thaddeus, Prendergast, Sophie Catherine, Burke, Louise, O’Connor, Cormac T., Ullah, Ihsan, O’Brien, Julie M., Hinchion, John A., Arnous, Samer, Kiernan, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589445/
https://www.ncbi.nlm.nih.gov/pubmed/37869216
http://dx.doi.org/10.1016/j.jaccas.2023.102027
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author Soh, Bing Wei Thaddeus
Prendergast, Sophie Catherine
Burke, Louise
O’Connor, Cormac T.
Ullah, Ihsan
O’Brien, Julie M.
Hinchion, John A.
Arnous, Samer
Kiernan, Thomas J.
author_facet Soh, Bing Wei Thaddeus
Prendergast, Sophie Catherine
Burke, Louise
O’Connor, Cormac T.
Ullah, Ihsan
O’Brien, Julie M.
Hinchion, John A.
Arnous, Samer
Kiernan, Thomas J.
author_sort Soh, Bing Wei Thaddeus
collection PubMed
description IgG4-related disease (IgG4-RD) is a new clinical entity characterized by lymphoplasmacytic lesions rich in IgG4-positive plasma cells. Myocardial involvement is extremely rare and not a typical cardiovascular manifestation of IgG4-RD. We report a rare case of IgG4-RD–associated myocardial mass causing severe aortic incompetence, successfully treated with surgery and corticosteroids. (Level of Difficulty: Intermediate.)
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spelling pubmed-105894452023-10-22 Severe Aortic Valvular Incompetence From IgG4-Related Disease: An Unusual Entity Soh, Bing Wei Thaddeus Prendergast, Sophie Catherine Burke, Louise O’Connor, Cormac T. Ullah, Ihsan O’Brien, Julie M. Hinchion, John A. Arnous, Samer Kiernan, Thomas J. JACC Case Rep Case Report IgG4-related disease (IgG4-RD) is a new clinical entity characterized by lymphoplasmacytic lesions rich in IgG4-positive plasma cells. Myocardial involvement is extremely rare and not a typical cardiovascular manifestation of IgG4-RD. We report a rare case of IgG4-RD–associated myocardial mass causing severe aortic incompetence, successfully treated with surgery and corticosteroids. (Level of Difficulty: Intermediate.) Elsevier 2023-09-15 /pmc/articles/PMC10589445/ /pubmed/37869216 http://dx.doi.org/10.1016/j.jaccas.2023.102027 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Soh, Bing Wei Thaddeus
Prendergast, Sophie Catherine
Burke, Louise
O’Connor, Cormac T.
Ullah, Ihsan
O’Brien, Julie M.
Hinchion, John A.
Arnous, Samer
Kiernan, Thomas J.
Severe Aortic Valvular Incompetence From IgG4-Related Disease: An Unusual Entity
title Severe Aortic Valvular Incompetence From IgG4-Related Disease: An Unusual Entity
title_full Severe Aortic Valvular Incompetence From IgG4-Related Disease: An Unusual Entity
title_fullStr Severe Aortic Valvular Incompetence From IgG4-Related Disease: An Unusual Entity
title_full_unstemmed Severe Aortic Valvular Incompetence From IgG4-Related Disease: An Unusual Entity
title_short Severe Aortic Valvular Incompetence From IgG4-Related Disease: An Unusual Entity
title_sort severe aortic valvular incompetence from igg4-related disease: an unusual entity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589445/
https://www.ncbi.nlm.nih.gov/pubmed/37869216
http://dx.doi.org/10.1016/j.jaccas.2023.102027
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