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The developmental hierarchy and scarcity of replicative slender trypanosomes in blood challenges their role in infection maintenance
The development of Trypanosoma brucei in its mammalian host is marked by a distinct morphological change as replicative “slender” forms differentiate into cell cycle arrested “stumpy” forms in a quorum-sensing-dependent manner. Although stumpy forms dominate chronic infections at the population leve...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589647/ https://www.ncbi.nlm.nih.gov/pubmed/37824530 http://dx.doi.org/10.1073/pnas.2306848120 |