Loss of PPARγ activity characterizes early protumorigenic stromal reprogramming and dictates the therapeutic window of opportunity

Although robustly expressed in the disease-free (DF) breast stroma, CD36 is consistently absent from the stroma surrounding invasive breast cancers (IBCs). In this study, we primarily observed CD36 expression in adipocytes and intralobular capillaries within the DF breast. Larger vessels concentrate...

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Detalles Bibliográficos
Autores principales: Caruso, Joseph A., Wang, Xianhong, Murrow, Lyndsay M., Rodriguez, Carlos Ivan, Chen-Tanyolac, Chira, Vu, Lisa, Chen, Yunn-Yi, Gascard, Philippe, Gartner, Zev J., Kerlikowske, Karla, Tlsty, Thea D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589683/
https://www.ncbi.nlm.nih.gov/pubmed/37816052
http://dx.doi.org/10.1073/pnas.2303774120

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