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Downregulation of apoptotic repressor AVEN exacerbates cardiac injury after myocardial infarction
Myocardial infarction (MI) is a leading cause of heart failure (HF), associated with morbidity and mortality worldwide. As an essential part of gene expression regulation, the role of alternative polyadenylation (APA) in post-MI HF remains elusive. Here, we revealed a global, APA-mediated, 3′ untran...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589712/ https://www.ncbi.nlm.nih.gov/pubmed/37816050 http://dx.doi.org/10.1073/pnas.2302482120 |