A Hospital-Wide Open-Label Cluster Crossover Pragmatic Comparative Effectiveness Randomized Trial Comparing Normal Saline to Ringer’s Lactate: Protocol and Statistical Analysis Plan of The FLUID Trial

BACKGROUND: Normal saline (NS) and Ringer’s lactate (RL) are the most common crystalloids given to hospitalized patients. Despite concern about possible harm associated with NS (eg, hyperchloremic metabolic acidosis, impaired kidney function, and death), few large multicenter randomized trials focus...

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Detalles Bibliográficos
Autores principales: Shaw, Julia F, Ouyang, Yongdong, Fergusson, Dean A, McArdle, Tracy, Martin, Claudio, Cook, Deborah, Graham, Ian D, Hawken, Steven, McCartney, Colin J L, Menon, Kusum, Saginur, Raphael, Seely, Andrew, Stiell, Ian, Fox-Robichaud, Alison, English, Shane, Marshall, John, Thavorn, Kednapa, Taljaard, Monica, McIntyre, Lauralyn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589831/
https://www.ncbi.nlm.nih.gov/pubmed/37801356
http://dx.doi.org/10.2196/51783

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