The splicing factor DHX38 enables retinal development through safeguarding genome integrity

DEAH-Box Helicase 38 (DHX38) is a pre-mRNA splicing factor and also a disease-causing gene of autosomal recessive retinitis pigmentosa (arRP). The role of DHX38 in the development and maintenance of the retina remains largely unknown. In this study, by using the dhx38 knockout zebrafish model, we de...

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Detalles Bibliográficos
Autores principales: Sun, Kui, Han, Yunqiao, Li, Jingzhen, Yu, Shanshan, Huang, Yuwen, Zhang, Yangjun, Reilly, Jamas, Tu, Jiayi, Gao, Pan, Jia, Danna, Chen, Xiang, Hu, Hualei, Ren, Mengmeng, Li, Pei, Luo, Jiong, Ren, Xiang, Zhang, Xianqin, Shu, Xinhua, Liu, Fei, Liu, Mugen, Tang, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589891/
https://www.ncbi.nlm.nih.gov/pubmed/37867960
http://dx.doi.org/10.1016/j.isci.2023.108103

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