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Elesclomol, a copper-transporting therapeutic agent targeting mitochondria: from discovery to its novel applications
Copper (Cu) is an essential element that is involved in a variety of biochemical processes. Both deficiency and accumulation of Cu are associated with various diseases; and a high amount of accumulated Cu in cells can be fatal. The production of reactive oxygen species (ROS), oxidative stress, and c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589935/ https://www.ncbi.nlm.nih.gov/pubmed/37864163 http://dx.doi.org/10.1186/s12967-023-04533-5 |