E3 ligase TRIM28 promotes anti-PD-1 resistance in non-small cell lung cancer by enhancing the recruitment of myeloid-derived suppressor cells

BACKGROUND: Alterations in several tripartite motif-containing (TRIM) family proteins have been implicated in the pathogenesis of lung cancer. TRIM28, a member of the TRIM E3 ligase family, has been associated with tumorigenesis, cell proliferation, and inflammation. However, little is known about T...

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Detalles Bibliográficos
Autores principales: Liang, Manman, Sun, Zhengui, Chen, Xingwu, Wang, Lijing, Wang, Hanli, Qin, Lilong, Zhao, Wenying, Geng, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589970/
https://www.ncbi.nlm.nih.gov/pubmed/37865804
http://dx.doi.org/10.1186/s13046-023-02862-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589970/
https://www.ncbi.nlm.nih.gov/pubmed/37865804
http://dx.doi.org/10.1186/s13046-023-02862-3

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