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E3 ligase TRIM28 promotes anti-PD-1 resistance in non-small cell lung cancer by enhancing the recruitment of myeloid-derived suppressor cells
BACKGROUND: Alterations in several tripartite motif-containing (TRIM) family proteins have been implicated in the pathogenesis of lung cancer. TRIM28, a member of the TRIM E3 ligase family, has been associated with tumorigenesis, cell proliferation, and inflammation. However, little is known about T...
Autores principales: | Liang, Manman, Sun, Zhengui, Chen, Xingwu, Wang, Lijing, Wang, Hanli, Qin, Lilong, Zhao, Wenying, Geng, Biao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589970/ https://www.ncbi.nlm.nih.gov/pubmed/37865804 http://dx.doi.org/10.1186/s13046-023-02862-3 |
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