Tau accumulation in degradative organelles is associated to lysosomal stress

Neurodegenerative disorders are characterized by the brain deposition of insoluble amyloidogenic proteins, such as α-synuclein or Tau, and the concomitant deterioration of cell functions such as the autophagy-lysosomal pathway (ALP). The ALP is involved in the degradation of intracellular macromolec...

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Detalles Bibliográficos
Autores principales: Piovesana, Ester, Magrin, Claudia, Ciccaldo, Matteo, Sola, Martina, Bellotto, Manolo, Molinari, Maurizio, Papin, Stéphanie, Paganetti, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590387/
https://www.ncbi.nlm.nih.gov/pubmed/37865674
http://dx.doi.org/10.1038/s41598-023-44979-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590387/
https://www.ncbi.nlm.nih.gov/pubmed/37865674
http://dx.doi.org/10.1038/s41598-023-44979-7

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