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Dopaminergic neurodegeneration in the substantia nigra is associated with olfactory dysfunction in mice models of Parkinson’s disease

Olfactory dysfunction represents a prodromal stage in Parkinson’s disease (PD). However, the mechanisms underlying hyposmia are not specified yet. In this study, we first observed an early olfactory dysfunction in mice with intragastric rotenone administration, consistent with dopaminergic neurons l...

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Detalles Bibliográficos
Autores principales: Yuan, Yu, Ma, Xizhen, Mi, Xiaoqing, Qu, Le, Liang, Meiyu, Li, Mengyu, Wang, Youcui, Song, Ning, Xie, Junxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590405/
https://www.ncbi.nlm.nih.gov/pubmed/37865662
http://dx.doi.org/10.1038/s41420-023-01684-8