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Dopaminergic neurodegeneration in the substantia nigra is associated with olfactory dysfunction in mice models of Parkinson’s disease
Olfactory dysfunction represents a prodromal stage in Parkinson’s disease (PD). However, the mechanisms underlying hyposmia are not specified yet. In this study, we first observed an early olfactory dysfunction in mice with intragastric rotenone administration, consistent with dopaminergic neurons l...
Autores principales: | Yuan, Yu, Ma, Xizhen, Mi, Xiaoqing, Qu, Le, Liang, Meiyu, Li, Mengyu, Wang, Youcui, Song, Ning, Xie, Junxia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590405/ https://www.ncbi.nlm.nih.gov/pubmed/37865662 http://dx.doi.org/10.1038/s41420-023-01684-8 |
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