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An innate granuloma eradicates an environmental pathogen using Gsdmd and Nos2

Granulomas often form around pathogens that cause chronic infections. Here, we discover an innate granuloma model in mice with an environmental bacterium called Chromobacterium violaceum. Granuloma formation not only successfully walls off, but also clears, the infection. The infected lesion can ari...

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Detalles Bibliográficos
Autores principales: Harvest, Carissa K., Abele, Taylor J., Yu, Chen, Beatty, Cole J., Amason, Megan E., Billman, Zachary P., DePrizio, Morgan A., Souza, Fernando W., Lacey, Carolyn A., Maltez, Vivien I., Larson, Heather N., McGlaughon, Benjamin D., Saban, Daniel R., Montgomery, Stephanie A., Miao, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590453/
https://www.ncbi.nlm.nih.gov/pubmed/37865673
http://dx.doi.org/10.1038/s41467-023-42218-1