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A comprehensive model for tRNA methylation modification studies

The molecular mechanism of N(7)‐methylguanosine (m(7)G)‐tRNA modification mediated by the methyltransferase like 1‐WD repeat domain 4 (METTL1–WDR4). Route A indicated that with WDR4 as the scaffold, METTL1 catalyzed G46 methylation modification after binding of the tRNA variable loop via its αC and...

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Detalles Bibliográficos
Autores principales: Weng, Qi, Zhang, Feng, Zheng, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590456/
https://www.ncbi.nlm.nih.gov/pubmed/37873513
http://dx.doi.org/10.1002/mco2.402

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