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Efficacy and Safety of Microwave Ablation Assisted by Ultrasound Fusion Imaging for Primary and Secondary Liver Cancers with a Diameter of 3–7 Cm

PURPOSE: To investigate the efficacy and safety of microwave ablation (MWA) assisted by ultrasound fusion imaging (FI) for primary and secondary liver cancers with a diameter of 3–7 cm. PATIENTS AND METHODS: A retrospective analysis was conducted on patients with primary and secondary liver cancers...

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Autores principales: Yang, Jing, Liang, Shuang, Liu, Huahui, Hu, Cai, Guan, Sainan, Kang, Haiyu, Xu, Erjiao, Yan, Ronghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590584/
https://www.ncbi.nlm.nih.gov/pubmed/37873028
http://dx.doi.org/10.2147/JHC.S424009
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author Yang, Jing
Liang, Shuang
Liu, Huahui
Hu, Cai
Guan, Sainan
Kang, Haiyu
Xu, Erjiao
Yan, Ronghua
author_facet Yang, Jing
Liang, Shuang
Liu, Huahui
Hu, Cai
Guan, Sainan
Kang, Haiyu
Xu, Erjiao
Yan, Ronghua
author_sort Yang, Jing
collection PubMed
description PURPOSE: To investigate the efficacy and safety of microwave ablation (MWA) assisted by ultrasound fusion imaging (FI) for primary and secondary liver cancers with a diameter of 3–7 cm. PATIENTS AND METHODS: A retrospective analysis was conducted on patients with primary and secondary liver cancers (3–7 cm) who underwent MWA with ultrasound FI assistance in our hospital from April 2020 to May 2022. Technical success, technique efficacy, local tumor progression (LTP), major complication, intrahepatic distant recurrence (IDR), and overall survival (OS) were assessed during the follow-up period. In addition, the ablation results of tumors between the medium-sized group (3.1–5.0 cm) and large-sized group (5.1–7.0 cm) were compared. RESULTS: 31 patients with 35 primary and secondary liver cancers were treated with MWA assisted by ultrasound FI. Complete ablation was achieved in 34 lesions with a technical success rate of 97.1%. Major complications occurred in 6.5% of patients (2/31), while no ablation-related deaths were reported. The median follow-up time of this study was 24 months (range:10 to 35 months). The technique efficacy rate was 97.1% (34/35), with LTP occurring in three lesions at a rate of 8.8% (3/34). The incidence of IDR was 38.7% (12/31) and the 2-year cumulative OS rate reached 96.7%. Moreover, there were no statistical differences in technique efficacy rate (p=0.286), LTP rate (p=0.328), major complication rate (p=0.503), IDR (p=0.857), and OS (p=0.118) between medium-sized group and large-sized group. CONCLUSION: Ultrasound FI-assisted MWA has the potential to be an effective and safe therapeutic strategy for primary and secondary liver cancers ranging from 3–7 cm in size.
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spelling pubmed-105905842023-10-23 Efficacy and Safety of Microwave Ablation Assisted by Ultrasound Fusion Imaging for Primary and Secondary Liver Cancers with a Diameter of 3–7 Cm Yang, Jing Liang, Shuang Liu, Huahui Hu, Cai Guan, Sainan Kang, Haiyu Xu, Erjiao Yan, Ronghua J Hepatocell Carcinoma Original Research PURPOSE: To investigate the efficacy and safety of microwave ablation (MWA) assisted by ultrasound fusion imaging (FI) for primary and secondary liver cancers with a diameter of 3–7 cm. PATIENTS AND METHODS: A retrospective analysis was conducted on patients with primary and secondary liver cancers (3–7 cm) who underwent MWA with ultrasound FI assistance in our hospital from April 2020 to May 2022. Technical success, technique efficacy, local tumor progression (LTP), major complication, intrahepatic distant recurrence (IDR), and overall survival (OS) were assessed during the follow-up period. In addition, the ablation results of tumors between the medium-sized group (3.1–5.0 cm) and large-sized group (5.1–7.0 cm) were compared. RESULTS: 31 patients with 35 primary and secondary liver cancers were treated with MWA assisted by ultrasound FI. Complete ablation was achieved in 34 lesions with a technical success rate of 97.1%. Major complications occurred in 6.5% of patients (2/31), while no ablation-related deaths were reported. The median follow-up time of this study was 24 months (range:10 to 35 months). The technique efficacy rate was 97.1% (34/35), with LTP occurring in three lesions at a rate of 8.8% (3/34). The incidence of IDR was 38.7% (12/31) and the 2-year cumulative OS rate reached 96.7%. Moreover, there were no statistical differences in technique efficacy rate (p=0.286), LTP rate (p=0.328), major complication rate (p=0.503), IDR (p=0.857), and OS (p=0.118) between medium-sized group and large-sized group. CONCLUSION: Ultrasound FI-assisted MWA has the potential to be an effective and safe therapeutic strategy for primary and secondary liver cancers ranging from 3–7 cm in size. Dove 2023-10-18 /pmc/articles/PMC10590584/ /pubmed/37873028 http://dx.doi.org/10.2147/JHC.S424009 Text en © 2023 Yang et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Yang, Jing
Liang, Shuang
Liu, Huahui
Hu, Cai
Guan, Sainan
Kang, Haiyu
Xu, Erjiao
Yan, Ronghua
Efficacy and Safety of Microwave Ablation Assisted by Ultrasound Fusion Imaging for Primary and Secondary Liver Cancers with a Diameter of 3–7 Cm
title Efficacy and Safety of Microwave Ablation Assisted by Ultrasound Fusion Imaging for Primary and Secondary Liver Cancers with a Diameter of 3–7 Cm
title_full Efficacy and Safety of Microwave Ablation Assisted by Ultrasound Fusion Imaging for Primary and Secondary Liver Cancers with a Diameter of 3–7 Cm
title_fullStr Efficacy and Safety of Microwave Ablation Assisted by Ultrasound Fusion Imaging for Primary and Secondary Liver Cancers with a Diameter of 3–7 Cm
title_full_unstemmed Efficacy and Safety of Microwave Ablation Assisted by Ultrasound Fusion Imaging for Primary and Secondary Liver Cancers with a Diameter of 3–7 Cm
title_short Efficacy and Safety of Microwave Ablation Assisted by Ultrasound Fusion Imaging for Primary and Secondary Liver Cancers with a Diameter of 3–7 Cm
title_sort efficacy and safety of microwave ablation assisted by ultrasound fusion imaging for primary and secondary liver cancers with a diameter of 3–7 cm
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590584/
https://www.ncbi.nlm.nih.gov/pubmed/37873028
http://dx.doi.org/10.2147/JHC.S424009
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