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Complications and associated risk factors after surgical management of proximal femoral fractures

AIMS: This work aimed at answering the following research questions: 1) What is the rate of mechanical complications, nonunion and infection for head/neck femoral fractures, intertrochanteric fractures, and subtrochanteric fractures in the elderly USA population? and 2) Which factors influence adver...

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Autores principales: Walter, Nike, Szymski, Dominik, Kurtz, Steven M., Lowenberg, David W., Alt, Volker, Lau, Edmund C., Rupp, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2023
Materias:
Hip
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590671/
https://www.ncbi.nlm.nih.gov/pubmed/37866820
http://dx.doi.org/10.1302/2633-1462.410.BJO-2023-0088.R1
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author Walter, Nike
Szymski, Dominik
Kurtz, Steven M.
Lowenberg, David W.
Alt, Volker
Lau, Edmund C.
Rupp, Markus
author_facet Walter, Nike
Szymski, Dominik
Kurtz, Steven M.
Lowenberg, David W.
Alt, Volker
Lau, Edmund C.
Rupp, Markus
author_sort Walter, Nike
collection PubMed
description AIMS: This work aimed at answering the following research questions: 1) What is the rate of mechanical complications, nonunion and infection for head/neck femoral fractures, intertrochanteric fractures, and subtrochanteric fractures in the elderly USA population? and 2) Which factors influence adverse outcomes? METHODS: Proximal femoral fractures occurred between 1 January 2009 and 31 December 2019 were identified from the Medicare Physician Service Records Data Base. The Kaplan-Meier method with Fine and Gray sub-distribution adaptation was used to determine rates for nonunion, infection, and mechanical complications. Semiparametric Cox regression model was applied incorporating 23 measures as covariates to identify risk factors. RESULTS: Union failure occured in 0.89% (95% confidence interval (CI) 0.83 to 0.95) after head/neck fracturs, in 0.92% (95% CI 0.84 to 1.01) after intertrochanteric fracture and in 1.99% (95% CI 1.69 to 2.33) after subtrochanteric fractures within 24 months. A fracture-related infection was more likely to occur after subtrochanteric fractures than after head/neck fractures (1.64% vs 1.59%, hazard ratio (HR) 1.01 (95% CI 0.87 to 1.17); p < 0.001) as well as after intertrochanteric fractures (1.64% vs 1.13%, HR 1.31 (95% CI 1.12 to 1.52); p < 0.001). Anticoagulant use, cerebrovascular disease, a concomitant fracture, diabetes mellitus, hypertension, obesity, open fracture, and rheumatoid disease was identified as risk factors. Mechanical complications after 24 months were most common after head/neck fractures with 3.52% (95% CI 3.41 to 3.64; currently at risk: 48,282). CONCLUSION: The determination of complication rates for each fracture type can be useful for informed patient-clinician communication. Risk factors for complications could be identified for distinct proximal femur fractures in elderly patients, which are accessible for therapeutical treatment in the management. Cite this article: Bone Jt Open 2023;4(10):801–807.
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spelling pubmed-105906712023-10-23 Complications and associated risk factors after surgical management of proximal femoral fractures Walter, Nike Szymski, Dominik Kurtz, Steven M. Lowenberg, David W. Alt, Volker Lau, Edmund C. Rupp, Markus Bone Jt Open Hip AIMS: This work aimed at answering the following research questions: 1) What is the rate of mechanical complications, nonunion and infection for head/neck femoral fractures, intertrochanteric fractures, and subtrochanteric fractures in the elderly USA population? and 2) Which factors influence adverse outcomes? METHODS: Proximal femoral fractures occurred between 1 January 2009 and 31 December 2019 were identified from the Medicare Physician Service Records Data Base. The Kaplan-Meier method with Fine and Gray sub-distribution adaptation was used to determine rates for nonunion, infection, and mechanical complications. Semiparametric Cox regression model was applied incorporating 23 measures as covariates to identify risk factors. RESULTS: Union failure occured in 0.89% (95% confidence interval (CI) 0.83 to 0.95) after head/neck fracturs, in 0.92% (95% CI 0.84 to 1.01) after intertrochanteric fracture and in 1.99% (95% CI 1.69 to 2.33) after subtrochanteric fractures within 24 months. A fracture-related infection was more likely to occur after subtrochanteric fractures than after head/neck fractures (1.64% vs 1.59%, hazard ratio (HR) 1.01 (95% CI 0.87 to 1.17); p < 0.001) as well as after intertrochanteric fractures (1.64% vs 1.13%, HR 1.31 (95% CI 1.12 to 1.52); p < 0.001). Anticoagulant use, cerebrovascular disease, a concomitant fracture, diabetes mellitus, hypertension, obesity, open fracture, and rheumatoid disease was identified as risk factors. Mechanical complications after 24 months were most common after head/neck fractures with 3.52% (95% CI 3.41 to 3.64; currently at risk: 48,282). CONCLUSION: The determination of complication rates for each fracture type can be useful for informed patient-clinician communication. Risk factors for complications could be identified for distinct proximal femur fractures in elderly patients, which are accessible for therapeutical treatment in the management. Cite this article: Bone Jt Open 2023;4(10):801–807. The British Editorial Society of Bone & Joint Surgery 2023-10-23 /pmc/articles/PMC10590671/ /pubmed/37866820 http://dx.doi.org/10.1302/2633-1462.410.BJO-2023-0088.R1 Text en © 2023 Author(s) et al. https://creativecommons.org/licenses/by-nc-nd/4.0/https://online.boneandjoint.org.uk/TDMThis is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Hip
Walter, Nike
Szymski, Dominik
Kurtz, Steven M.
Lowenberg, David W.
Alt, Volker
Lau, Edmund C.
Rupp, Markus
Complications and associated risk factors after surgical management of proximal femoral fractures
title Complications and associated risk factors after surgical management of proximal femoral fractures
title_full Complications and associated risk factors after surgical management of proximal femoral fractures
title_fullStr Complications and associated risk factors after surgical management of proximal femoral fractures
title_full_unstemmed Complications and associated risk factors after surgical management of proximal femoral fractures
title_short Complications and associated risk factors after surgical management of proximal femoral fractures
title_sort complications and associated risk factors after surgical management of proximal femoral fractures
topic Hip
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590671/
https://www.ncbi.nlm.nih.gov/pubmed/37866820
http://dx.doi.org/10.1302/2633-1462.410.BJO-2023-0088.R1
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