RIPK3 promotes hantaviral replication by restricting JAK-STAT signaling without triggering necroptosis

Hantaan virus (HTNV) is a rodent-borne virus that causes hemorrhagic fever with renal syndrome (HFRS), resulting in a high mortality rate of 15%. Interferons (IFNs) play a critical role in the anti-hantaviral immune response, and IFN pretreatment efficiently restricts HTNV infection by triggering th...

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Detalles Bibliográficos
Autores principales: Si, Yue, Zhang, Haijun, Zhou, Ziqing, Zhu, Xudong, Yang, Yongheng, Liu, He, Zhang, Liang, Cheng, Linfeng, Wang, Kerong, Ye, Wei, Lv, Xin, Zhang, Xijing, Hou, Wugang, Zhao, Gang, Lei, Yingfeng, Zhang, Fanglin, Ma, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590702/
https://www.ncbi.nlm.nih.gov/pubmed/37633447
http://dx.doi.org/10.1016/j.virs.2023.08.006

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