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Isoliquiritigenin modulates the activity of LTS and non-LTS cells in the ventrolateral preoptic area via GABA(A) receptors

OBJECTIVE: Isoliquiritigenin (ILTG) is a chalcone compound that exhibits hypnotic effects via gamma-aminobutyric acid type A (GABA(A)) receptors. The ventrolateral preoptic area (VLPO) is a sleep-promoting center that contains a large number of GABA-releasing cells. There are two cell types in the V...

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Detalles Bibliográficos
Autores principales: Fan, Sumei, Jin, Qiaoling, Zhang, Pingping, Xu, Dejiao, Cheng, Juan, Wang, Liecheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590785/
https://www.ncbi.nlm.nih.gov/pubmed/37876454
http://dx.doi.org/10.1016/j.heliyon.2023.e20620