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LRRK2 G2019S promotes astrocytic inflammation induced by oligomeric α-synuclein through NF-κB pathway

Parkinson’s disease (PD) is characterized by the irreversible loss of dopaminergic neurons and the accumulation of α-synuclein in Lewy bodies. The oligomeric α-synuclein (O-αS) is the most toxic form of α-synuclein species, and it has been reported to be a robust inflammatory mediator. Mutations in...

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Detalles Bibliográficos
Autores principales:	He, Kai-Jie, Zhang, Jin-Bao, Liu, Jun-Yi, Zhao, Feng-Lun, Yao, Xiao-Yu, Tang, Yu-Ting, Zhang, Jin-Ru, Cheng, Xiao-Yu, Hu, Li-Fang, Wang, Fen, Liu, Chun-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590863/ https://www.ncbi.nlm.nih.gov/pubmed/37876795 http://dx.doi.org/10.1016/j.isci.2023.108130

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