Cargando…

Co-folding and RNA activation of poliovirus 3C(pro) polyprotein precursors

Positive-strand RNA viruses use long open reading frames to express large polyproteins that are processed into individual proteins by viral proteases. Polyprotein processing is highly regulated and yields intermediate species with different functions than the fully processed proteins, increasing the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Campagnola, Grace, Peersen, Olve
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590986/ https://www.ncbi.nlm.nih.gov/pubmed/37717698 http://dx.doi.org/10.1016/j.jbc.2023.105258

Ejemplares similares

The SARS-CoV nsp12 Polymerase Active Site Is Tuned for Large-Genome Replication
por: Campagnola, Grace, et al.
Publicado: (2022)

Superdiffusive motion of membrane-targeting C2 domains
por: Campagnola, Grace, et al.
Publicado: (2015)

Structures of Coxsackievirus, Rhinovirus, and Poliovirus Polymerase Elongation Complexes Solved by Engineering RNA Mediated Crystal Contacts
por: Gong, Peng, et al.
Publicado: (2013)

Assessing the Potential of Folded Globular Polyproteins As Hydrogel Building Blocks
por: da Silva, Marcelo A., et al.
Publicado: (2016)

A Comprehensive Superposition of Viral Polymerase Structures
por: Peersen, Olve B.
Publicado: (2019)

Viral precursor polyproteins: keys of regulation from replication to maturation
por: Yost, Samantha A, et al.
Publicado: (2013)

Polyprotein cleavage mechanism of SARS CoV M(pro) and chemical modification of the octapeptide
por: Du, Qi-Shi, et al.
Publicado: (2004)

SARS-CoV-2 polyprotein substrate regulates the stepwise M(pro) cleavage reaction
por: Narwal, Manju, et al.
Publicado: (2023)

Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine
por: Martínez-Sobrido, Luis, et al.
Publicado: (2018)

Polyproteins in structural biology
por: Crépin, Thibaut, et al.
Publicado: (2015)

Avibirnavirus VP4 Protein Is a Phosphoprotein and Partially Contributes to the Cleavage of Intermediate Precursor VP4-VP3 Polyprotein
por: Wang, Sanying, et al.
Publicado: (2015)

The mechanism of RNA recombination in poliovirus
por: Kirkegaard, Karla, et al.
Publicado: (1986)

Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro
por: Yadav, Ruchi, et al.
Publicado: (2022)

Hepatitis E virus RNA replication polyprotein: taking structural biology seriously
por: Fieulaine, Sonia, et al.
Publicado: (2023)

LAMPA, LArge Multidomain Protein Annotator, and its application to RNA virus polyproteins
por: Gulyaeva, Anastasia A, et al.
Publicado: (2020)

Processing of the Coronavirus MHV-JHM Polymerase Polyprotein: Identification of Precursors and Proteolytic Products Spanning 400 Kilodaltons of ORF1a()
por: Schiller, Jennifer J., et al.
Publicado: (1998)

Efficient self-assembly and protective efficacy of infectious bursal disease virus-like particles by a recombinant baculovirus co-expressing precursor polyprotein and VP4
por: Lee, Hyun-Jeong, et al.
Publicado: (2015)

The dynein light chain protein Tda2 functions as a dimerization engine to regulate actin capping protein during endocytosis
por: Lamb, Andrew K., et al.
Publicado: (2021)

Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites
por: Shannon, Ashleigh, et al.
Publicado: (2020)

Biosynthesis of pro-C3, a precursor of the third component of complement
Publicado: (1977)

The RNA-Binding Site of Poliovirus 3C Protein Doubles as a Phosphoinositide-Binding Domain
por: Shengjuler, Djoshkun, et al.
Publicado: (2017)

Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis
por: Shannon, Ashleigh, et al.
Publicado: (2020)

Multiprotein Complex Production in Insect Cells by Using Polyproteins
por: Nie, Yan, et al.
Publicado: (2013)

Polyprotein Processing as a Determinant for In Vitro Activity of Semliki Forest Virus Replicase
por: Pietilä, Maija K., et al.
Publicado: (2017)

The Autocatalytic Release of a Putative RNA Virus Transcription Factor from Its Polyprotein Precursor Involves Two Paralogous Papain-like Proteases That Cleave the Same Peptide Bond
por: Ziebuhr, John, et al.
Publicado: (2001)

Co-Circulation and Evolution of Polioviruses and Species C Enteroviruses in a District of Madagascar
por: Rakoto-Andrianarivelo, Mala, et al.
Publicado: (2007)

Generation of Unique Poliovirus RNA Replication Organelles
por: Richards, Alexsia L., et al.
Publicado: (2014)

Altering an Artificial Gagpolnef Polyprotein and Mode of ENV Co-Administration Affects the Immunogenicity of a Clade C HIV DNA Vaccine
por: Böckl, Katharina, et al.
Publicado: (2012)

Vemurafenib Inhibits Acute and Chronic Enterovirus Infection by Affecting Cellular Kinase Phosphatidylinositol 4-Kinase Type IIIβ
por: Laajala, Mira, et al.
Publicado: (2023)

Insights into Polyprotein Processing and RNA-Protein Interactions in Foot-and-Mouth Disease Virus Genome Replication
por: Pierce, Danielle M., et al.
Publicado: (2023)

Role of cleavage at the core-E1 junction of hepatitis C virus polyprotein in viral morphogenesis
por: Pène, Véronique, et al.
Publicado: (2017)

Recombination between Polioviruses and Co-Circulating Coxsackie A Viruses: Role in the Emergence of Pathogenic Vaccine-Derived Polioviruses
por: Jegouic, Sophie, et al.
Publicado: (2009)

Identification of Cleavage Sites Recognized by the 3C-Like Cysteine Protease within the Two Polyproteins of Strawberry Mottle Virus
por: Mann, Krin S., et al.
Publicado: (2017)

Direct detection of polioviruses using a recombinant poliovirus receptor
por: Gerloff, Nancy, et al.
Publicado: (2021)

Anti-dengue drug: viral polyprotein, a potential target
por: Mahmood, Syed Uzair, et al.
Publicado: (2016)

A review on HCV inhibitors: Significance of non-structural polyproteins
por: Ganta, Narayana Murthy, et al.
Publicado: (2019)

Enzymatic biosynthesis and immobilization of polyprotein verified at the single-molecule level
por: Deng, Yibing, et al.
Publicado: (2019)

Conformational Ensemble of the Poliovirus 3CD Precursor Observed by MD Simulations and Confirmed by SAXS: A Strategy to Expand the Viral Proteome?
por: Moustafa, Ibrahim M., et al.
Publicado: (2015)

Antiviral activity of recombinant ankyrin targeted to the capsid domain of HIV-1 Gag polyprotein
por: Nangola, Sawitree, et al.
Publicado: (2012)

Biochemical characterization of the fidelity of poliovirus RNA-dependent RNA polymerase
por: Freistadt, Marion S, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_ep9iuqpdjqfilrq5fv92gmhghg