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Mechanistic characterization of disulfide bond reduction of an ERAD substrate mediated by cooperation between ERdj5 and BiP

Endoplasmic reticulum (ER)-associated degradation (ERAD) is a protein quality control process that eliminates misfolded proteins from the ER. DnaJ homolog subfamily C member 10 (ERdj5) is a protein disulfide isomerase family member that accelerates ERAD by reducing disulfide bonds of aberrant protei...

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Detalles Bibliográficos
Autores principales: Cai, Xiaohan, Ito, Shogo, Noi, Kentaro, Inoue, Michio, Ushioda, Ryo, Kato, Yukinari, Nagata, Kazuhiro, Inaba, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591012/
https://www.ncbi.nlm.nih.gov/pubmed/37739037
http://dx.doi.org/10.1016/j.jbc.2023.105274