Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity

Immunophenotyping of the tumor microenvironment (TME) is essential for enhancing immunotherapy efficacy. However, strategies for characterizing the TME exhibit significant heterogeneity. Here, we show that endoplasmic reticular oxidoreductase-1α (ERO1A) mediates an immune-suppressive TME and attenua...

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Detalles Bibliográficos
Autores principales: Liu, Lihui, Li, Sini, Qu, Yan, Bai, Hua, Pan, Xiangyu, Wang, Jian, Wang, Zhijie, Duan, Jianchun, Zhong, Jia, Wan, Rui, Fei, Kailun, Xu, Jiachen, Yuan, Li, Wang, Chao, Xue, Pei, Zhang, Xue, Ma, Zixiao, Wang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591028/
https://www.ncbi.nlm.nih.gov/pubmed/37769655
http://dx.doi.org/10.1016/j.xcrm.2023.101206

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