SPOTlight on GLOW

The GLOW randomized double-blind phase 3 trial(1) shows that Claudin-18.2 targeting antibody zolbetuximab combined with capecitabine and oxaliplatin improves outcome compared to placebo and chemotherapy as first-line treatment in Claudin-18.2-positive, HER2-negative gastric or gastroesophageal junct...

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Detalles Bibliográficos
Autores principales: Derks, Sarah, van Laarhoven, Hanneke W.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591046/
https://www.ncbi.nlm.nih.gov/pubmed/37852180
http://dx.doi.org/10.1016/j.xcrm.2023.101233
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author Derks, Sarah
van Laarhoven, Hanneke W.M.
author_facet Derks, Sarah
van Laarhoven, Hanneke W.M.
author_sort Derks, Sarah
collection PubMed
description The GLOW randomized double-blind phase 3 trial(1) shows that Claudin-18.2 targeting antibody zolbetuximab combined with capecitabine and oxaliplatin improves outcome compared to placebo and chemotherapy as first-line treatment in Claudin-18.2-positive, HER2-negative gastric or gastroesophageal junction adenocarcinomas.
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spelling pubmed-105910462023-10-24 SPOTlight on GLOW Derks, Sarah van Laarhoven, Hanneke W.M. Cell Rep Med Spotlight The GLOW randomized double-blind phase 3 trial(1) shows that Claudin-18.2 targeting antibody zolbetuximab combined with capecitabine and oxaliplatin improves outcome compared to placebo and chemotherapy as first-line treatment in Claudin-18.2-positive, HER2-negative gastric or gastroesophageal junction adenocarcinomas. Elsevier 2023-10-17 /pmc/articles/PMC10591046/ /pubmed/37852180 http://dx.doi.org/10.1016/j.xcrm.2023.101233 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Spotlight
Derks, Sarah
van Laarhoven, Hanneke W.M.
SPOTlight on GLOW
title SPOTlight on GLOW
title_full SPOTlight on GLOW
title_fullStr SPOTlight on GLOW
title_full_unstemmed SPOTlight on GLOW
title_short SPOTlight on GLOW
title_sort spotlight on glow
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591046/
https://www.ncbi.nlm.nih.gov/pubmed/37852180
http://dx.doi.org/10.1016/j.xcrm.2023.101233
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