Cargando…

Replenishing decoy extracellular vesicles inhibits phenotype remodeling of tissue-resident cells in inflammation-driven arthritis

The interleukin 6 (IL6) signaling pathway plays pleiotropic roles in regulating the inflammatory milieu that contributes to arthritis development. Here, we show that activation of IL6 trans-signaling induces phenotypic transitions in tissue-resident cells toward an inflammatory state. The establishm...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Mengmeng, Wang, Ke, Wei, Xiaoyu, Gong, Xiaoshan, Tang, Hao, Xue, Hao, Wang, Jing, Yin, Pengbin, Zhang, Licheng, Ma, Zaisong, Dou, Ce, Dong, Shiwu, Xu, Jianzhong, Luo, Fei, Ma, Qinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591050/
https://www.ncbi.nlm.nih.gov/pubmed/37852176
http://dx.doi.org/10.1016/j.xcrm.2023.101228