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NTRK rearranged sarcoma of the bone. Role for larotrectinib in the neoadjuvant setting of an ultra-rare tumor: a case report

Background: Neurotrophic tyrosine receptor kinase (NTRK) gene-fusion targeted molecules revolutionized the paradigm of treatment of a limited subgroup of cancers of various histologies. Entrectinib and larotrectinib obtained unprecedented response rates in patients with cancer harboring NTRK rearran...

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Detalles Bibliográficos
Autores principales: Palmerini, Emanuela, Frega, Giorgio, Gambarotti, Marco, Frisoni, Tommaso, Cesari, Marilena, Bazzocchi, Alberto, Miceli, Marco, Donati, Davide Maria, Fanti, Stefano, Nanni, Cristina, Benini, Stefania, Longhi, Alessandra, Paioli, Anna, Marrari, Andrea, Hakim, Rossella, Righi, Alberto, Ibrahim, Toni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591071/
https://www.ncbi.nlm.nih.gov/pubmed/37876963
http://dx.doi.org/10.3389/fonc.2023.1252359