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Brucellae as resilient intracellular pathogens: epidemiology, host–pathogen interaction, recent genomics and proteomics approaches, and future perspectives

Brucellosis is considered one of the most hazardous zoonotic diseases all over the world. It causes formidable economic losses in developed and developing countries. Despite the significant attempts to get rid of Brucella pathogens in many parts of the world, the disease continues to spread widely....

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Autores principales: Dawood, Ali Sobhy, Elrashedy, Alyaa, Nayel, Mohamed, Salama, Akram, Guo, Aizhen, Zhao, Gang, Algharib, Samah Attia, Zaghawa, Ahmed, Zubair, Muhammed, Elsify, Ahmed, Mousa, Walid, Luo, Wanhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591102/
https://www.ncbi.nlm.nih.gov/pubmed/37876633
http://dx.doi.org/10.3389/fvets.2023.1255239
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author Dawood, Ali Sobhy
Elrashedy, Alyaa
Nayel, Mohamed
Salama, Akram
Guo, Aizhen
Zhao, Gang
Algharib, Samah Attia
Zaghawa, Ahmed
Zubair, Muhammed
Elsify, Ahmed
Mousa, Walid
Luo, Wanhe
author_facet Dawood, Ali Sobhy
Elrashedy, Alyaa
Nayel, Mohamed
Salama, Akram
Guo, Aizhen
Zhao, Gang
Algharib, Samah Attia
Zaghawa, Ahmed
Zubair, Muhammed
Elsify, Ahmed
Mousa, Walid
Luo, Wanhe
author_sort Dawood, Ali Sobhy
collection PubMed
description Brucellosis is considered one of the most hazardous zoonotic diseases all over the world. It causes formidable economic losses in developed and developing countries. Despite the significant attempts to get rid of Brucella pathogens in many parts of the world, the disease continues to spread widely. Recently, many attempts proved to be effective for the prevention and control of highly contagious bovine brucellosis, which could be followed by others to achieve a prosperous future without rampant Brucella pathogens. In this study, the updated view for worldwide Brucella distribution, possible predisposing factors for emerging Brucella pathogens, immune response and different types of Brucella vaccines, genomics and proteomics approaches incorporated recently in the field of brucellosis, and future perspectives for prevention and control of bovine brucellosis have been discussed comprehensively. So, the current study will be used as a guide for researchers in planning their future work, which will pave the way for a new world without these highly contagious pathogens that have been infecting and threatening the health of humans and terrestrial animals.
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spelling pubmed-105911022023-10-24 Brucellae as resilient intracellular pathogens: epidemiology, host–pathogen interaction, recent genomics and proteomics approaches, and future perspectives Dawood, Ali Sobhy Elrashedy, Alyaa Nayel, Mohamed Salama, Akram Guo, Aizhen Zhao, Gang Algharib, Samah Attia Zaghawa, Ahmed Zubair, Muhammed Elsify, Ahmed Mousa, Walid Luo, Wanhe Front Vet Sci Veterinary Science Brucellosis is considered one of the most hazardous zoonotic diseases all over the world. It causes formidable economic losses in developed and developing countries. Despite the significant attempts to get rid of Brucella pathogens in many parts of the world, the disease continues to spread widely. Recently, many attempts proved to be effective for the prevention and control of highly contagious bovine brucellosis, which could be followed by others to achieve a prosperous future without rampant Brucella pathogens. In this study, the updated view for worldwide Brucella distribution, possible predisposing factors for emerging Brucella pathogens, immune response and different types of Brucella vaccines, genomics and proteomics approaches incorporated recently in the field of brucellosis, and future perspectives for prevention and control of bovine brucellosis have been discussed comprehensively. So, the current study will be used as a guide for researchers in planning their future work, which will pave the way for a new world without these highly contagious pathogens that have been infecting and threatening the health of humans and terrestrial animals. Frontiers Media S.A. 2023-10-09 /pmc/articles/PMC10591102/ /pubmed/37876633 http://dx.doi.org/10.3389/fvets.2023.1255239 Text en Copyright © 2023 Dawood, Elrashedy, Nayel, Salama, Guo, Zhao, Algharib, Zaghawa, Zubair, Elsify, Mousa and Luo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Dawood, Ali Sobhy
Elrashedy, Alyaa
Nayel, Mohamed
Salama, Akram
Guo, Aizhen
Zhao, Gang
Algharib, Samah Attia
Zaghawa, Ahmed
Zubair, Muhammed
Elsify, Ahmed
Mousa, Walid
Luo, Wanhe
Brucellae as resilient intracellular pathogens: epidemiology, host–pathogen interaction, recent genomics and proteomics approaches, and future perspectives
title Brucellae as resilient intracellular pathogens: epidemiology, host–pathogen interaction, recent genomics and proteomics approaches, and future perspectives
title_full Brucellae as resilient intracellular pathogens: epidemiology, host–pathogen interaction, recent genomics and proteomics approaches, and future perspectives
title_fullStr Brucellae as resilient intracellular pathogens: epidemiology, host–pathogen interaction, recent genomics and proteomics approaches, and future perspectives
title_full_unstemmed Brucellae as resilient intracellular pathogens: epidemiology, host–pathogen interaction, recent genomics and proteomics approaches, and future perspectives
title_short Brucellae as resilient intracellular pathogens: epidemiology, host–pathogen interaction, recent genomics and proteomics approaches, and future perspectives
title_sort brucellae as resilient intracellular pathogens: epidemiology, host–pathogen interaction, recent genomics and proteomics approaches, and future perspectives
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591102/
https://www.ncbi.nlm.nih.gov/pubmed/37876633
http://dx.doi.org/10.3389/fvets.2023.1255239
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