CRISPR/Cas9-Mediated Generation of COL7A1-Deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa

OBJECTIVE: Recessive dystrophic epidermolysis bullosa (RDEB) is a genetic skin fragility and ultimately lethal blistering disease caused by mutations in the COL7A1 gene which is responsible for coding type VII collagen. Investigating the pathological mechanisms and novel candidate therapies for RDEB...

Descripción completa

Detalles Bibliográficos
Autores principales: Alipour, Farzad, Ahmadraji, Mana, Yektadoust, Elham, Mohammadi, Parvaneh, Baharvand, Hossein, Basiri, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591263/
https://www.ncbi.nlm.nih.gov/pubmed/37865875
http://dx.doi.org/10.22074/CELLJ.2023.1989321.1225

Ejemplares similares

Ejemplares similares