Orthogonal Enzyme–Substrate Design Strategy for Discovery of Human Protein Palmitoyltransferase Substrates

[Image: see text] Protein palmitoylation, with more than 5000 substrates, is the most prevalent form of protein lipidation. Palmitoylated proteins participate in almost all areas of cellular physiology and have been linked to several human diseases. Twenty-three zDHHC enzymes catalyze protein palmit...

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Detalles Bibliográficos
Autores principales: Puthenveetil, Robbins, Auger, Shelby A., Gómez-Navarro, Natalia, Rana, Mitra Shumsher, Das, Riki, Healy, Liam Brendan, Suazo, Kiall F., Shi, Zhen-Dan, Swenson, Rolf E., Distefano, Mark D., Banerjee, Anirban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591334/
https://www.ncbi.nlm.nih.gov/pubmed/37774000
http://dx.doi.org/10.1021/jacs.3c04359

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