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Tumor cell-induced platelet aggregation accelerates hematogenous metastasis of malignant melanoma by triggering macrophage recruitment

BACKGROUND: Tumor cell-induced platelet aggregation (TCIPA) is not only a recognized mechanism for paraneoplastic thrombocytosis but also a potential breakthrough alternative for a low response to immune checkpoint inhibitors (ICIs) in hematogenous metastasis of malignant melanoma (MM). However, the...

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Detalles Bibliográficos
Autores principales: Chen, Yuyi, Zhou, Jie, Liu, Zishen, Wu, Tongtong, Li, Shumeng, Zhang, Yutong, Yin, Xiaohui, Yang, Guowang, Zhang, Ganlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591353/
https://www.ncbi.nlm.nih.gov/pubmed/37872588
http://dx.doi.org/10.1186/s13046-023-02856-1