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Bifidobacterium bifidum and Lactobacillus paracasei alleviate sarcopenia and cognitive impairment in aged mice by regulating gut microbiota-mediated AKT, NF-κB, and FOXO3a signaling pathways

Sarcopenia is closely associated with gut dysbiosis. Probiotics alleviate gut dysbiosis. Therefore, we selected probiotics Lactobacillus paracasei P62 (Lp) and Bifidobacterium bifidum P61 (Bb), which suppressed muscle RING-finger protein-1 (MuRF1) expression and NF-κB activation in C2C12 cells, and...

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Detalles Bibliográficos
Autores principales:	Baek, Ji-Su, Shin, Yoon-Jung, Ma, Xiaoyang, Park, Hee-Seo, Hwang, Yun-Ha, Kim, Dong-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591382/ https://www.ncbi.nlm.nih.gov/pubmed/37872562 http://dx.doi.org/10.1186/s12979-023-00381-5

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