Comparison of methylation estimates obtained via MinION nanopore sequencing and sanger bisulfite sequencing in the TRPA1 promoter region

BACKGROUND: Bisulfite sequencing has long been considered the gold standard for measuring DNA methylation at single CpG resolution. However, in recent years several new approaches like nanopore sequencing have been developed due to hints for a partial error-proneness of bisulfite sequencing. Since t...

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Detalles Bibliográficos
Autores principales: Gombert, Sara, Jahn, Kirsten, Pathak, Hansi, Burkert, Alexandra, Schmidt, Gunnar, Wiehlmann, Lutz, Davenport, Colin, Brändl, Björn, Müller, Franz-Josef, Leffler, Andreas, Deest, Maximilian, Frieling, Helge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591399/
https://www.ncbi.nlm.nih.gov/pubmed/37872581
http://dx.doi.org/10.1186/s12920-023-01694-6

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