Cargando…

A bioinformatic analysis of the role of TP53 status on the infiltration of CD8(+) T cells into the tumor microenvironment

CD8(+) T cells play basic roles in the immune system in a tumor microenvironment (TME) to fight cancer. Several reports have suggested signs of the involvement of tumor protein p53 (TP53) in a complex immune system network. Moreover, our previous research indicated that TP53 orchestrates the polariz...

Descripción completa

Detalles Bibliográficos
Autores principales:	El-Arabey, A.A., Abdel-Hamied, H.E., Awadalla, M.E., Alosaimi, B., Almanaa, T.N., Al-Shouli, S.T., Modafer, Y.A., Alhamdi, H.W., Abdalla, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Associação Brasileira de Divulgação Científica 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591486/ https://www.ncbi.nlm.nih.gov/pubmed/37878888 http://dx.doi.org/10.1590/1414-431X2023e12970

Ejemplares similares

Revisiting macrophages in ovarian cancer microenvironment: development, function and interaction
por: El-Arabey, Amr Ahmed, et al.
Publicado: (2023)

Molecular dynamic and bioinformatic studies of metformin-induced ACE2 phosphorylation in the presence of different SARS-CoV-2 S protein mutations
por: El-Arabey, Amr Ahmed, et al.
Publicado: (2023)

Metformin as a promising target for DPP4 expression: computational modeling and experimental validation
por: El-Arabey, Amr Ahmed, et al.
Publicado: (2023)

TP3, an antimicrobial peptide, inhibits infiltration and motility of glioblastoma cells via modulating the tumor microenvironment
por: Chen, Ying‐Fa, et al.
Publicado: (2020)

Intronic TP53 Polymorphisms Are Associated with Increased Δ133TP53 Transcript, Immune Infiltration and Cancer Risk
por: Eiholzer, Ramona A., et al.
Publicado: (2020)

Histone lysine methylation patterns in prostate cancer microenvironment infiltration: Integrated bioinformatic analysis and histological validation
por: Quan, Yongjun, et al.
Publicado: (2022)

Immune Cell Infiltration and Identifying Genes of Prognostic Value in the Papillary Renal Cell Carcinoma Microenvironment by Bioinformatics Analysis
por: Liu, Ting, et al.
Publicado: (2020)

Identification of Tumor Microenvironment Scoring Scheme Based on Bioinformatics Analysis of Immune Cell Infiltration Pattern of Ovarian Cancer
por: Huo, Xiao, et al.
Publicado: (2022)

Molecular Subtype Classification of Postmenopausal Osteoporosis and Immune Infiltration Microenvironment Based on Bioinformatics Analysis of Osteoclast-Regulatory Genes
por: Gong, Yining, et al.
Publicado: (2023)

New Insight of OCT2 Regulation as Mediator for Cisplatin- Induced Nephrotoxicity
por: EL-Arabey, Amr Ahmed, et al.
Publicado: (2017)

Neuropilin-1 may be responsible for retinal findings in patients with COVID-19
por: El‑Arabey, Amr Ahmed, et al.
Publicado: (2021)

Transplacental transmission of SARS-CoV-2 infection via NRP1
por: El-Arabey, Amr Ahmed, et al.
Publicado: (2021)

Cardiovascular complications in the post-acute COVID-19 syndrome: A novel perspective down the road
por: El-Arabey, Amr Ahmed, et al.
Publicado: (2022)

Comprehensive bioinformatics analysis of the TP53 signaling pathway in Wilms’ tumor
por: He, Changjing, et al.
Publicado: (2020)

The role of tumor-infiltrating B cells in the tumor microenvironment of hepatocellular carcinoma and its prognostic value: a bioinformatics analysis
por: Zou, Jixue, et al.
Publicado: (2022)

MERS-CoV infection is associated with downregulation of genes encoding Th1 and Th2 cytokines/chemokines and elevated inflammatory innate immune response in the lower respiratory tract
por: Alosaimi, B., et al.
Publicado: (2020)

Erratum to comprehensive bioinformatics analysis of the TP53 signaling pathway in Wilms’ tumor
por: He, Changjing, et al.
Publicado: (2021)

Identification of Novel Characteristics in TP53-Mutant Hepatocellular Carcinoma Using Bioinformatics
por: Yang, Yang, et al.
Publicado: (2022)

Are the new SARS-CoV-2 variants resistant against the vaccine?
por: Abdalla, Mohnad, et al.
Publicado: (2021)

A bioinformatic analysis study of m(7)G regulator-mediated methylation modification patterns and tumor microenvironment infiltration in glioblastoma
por: Wu, Xinrui, et al.
Publicado: (2022)

Regulatory T Cells: Barriers of Immune Infiltration Into the Tumor Microenvironment
por: Scott, Ellen N., et al.
Publicado: (2021)

Differences in genetics and microenvironment of lung adenocarcinoma patients with or without TP53 mutation
por: Zeng, Dejun, et al.
Publicado: (2021)

Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma
por: Koirala, Pratistha, et al.
Publicado: (2016)

Metformin: Ongoing Journey with Superdrug Revolution
por: EL-Arabey, Amr Ahmed, et al.
Publicado: (2019)

The immune cell infiltrate in the tumour microenvironment of phaeochromocytomas and paragangliomas
por: Tufton, N, et al.
Publicado: (2022)

Bioinformatics-Led Discovery of Osteoarthritis Biomarkers and Inflammatory Infiltrates
por: Hu, Xinyue, et al.
Publicado: (2022)

Pro-Inflammatory Microenvironment Modulates the Transfer of Mutated TP53 Mediated by Tumor Exosomes
por: Domenis, Rossana, et al.
Publicado: (2021)

Bioinformatics Analysis of Prognostic Tumor Microenvironment-Related Genes in the Tumor Microenvironment of Hepatocellular Carcinoma
por: Tian, Zongbiao, et al.
Publicado: (2020)

The relationship of TP53 R72P polymorphism to disease outcome and TP53 mutation in myelodysplastic syndromes
por: McGraw, K L, et al.
Publicado: (2015)

Efficacy and Safety of Adding Low-Dose Isotretinoin to Itraconazole in the Treatment of Chronic Recurrent Dermatophytosis among Sample of Iraqi Patients: An Open-Labelled Therapeutic Clinical Comparative Study
por: Alhamdi, Dooha K., et al.
Publicado: (2022)

TP53 Mutation Infers a Poor Prognosis and Is Correlated to Immunocytes Infiltration in Breast Cancer
por: Zhang, Ziwen, et al.
Publicado: (2021)

TP53 mutation-associated immune infiltration and a novel risk score model in HNSCC
por: Kong, Weili, et al.
Publicado: (2022)

MicroRNAs, TGF-β signaling, and the inflammatory microenvironment in cancer
por: Guo, Lingling, et al.
Publicado: (2015)

Integrated bioinformatics analyses identifying key transcriptomes correlated with prognosis and immune infiltrations in lung squamous cell carcinoma
por: Alghamdi, Rana A., et al.
Publicado: (2023)

TpTe and TpTe/QT: novel markers to predict sudden cardiac death in ESRD?
por: Saour, Basil M., et al.
Publicado: (2018)

Pan-cancer classification of single cells in the tumour microenvironment
por: Nofech-Mozes, Ido, et al.
Publicado: (2023)

Bioinformatic Dissecting of TP53 Regulation Pathway Underlying Butyrate-induced Histone Modification in Epigenetic Regulation
por: Li, Cong-Jun, et al.
Publicado: (2014)

B cell infiltration is highly associated with prognosis and an immune-infiltrated tumor microenvironment in neuroblastoma
por: Schaafsma, Evelien, et al.
Publicado: (2021)

Tumor microenvironment in triple-negative breast cancer: the correlation of tumor-associated macrophages and tumor-infiltrating lymphocytes
por: Kuroda, H., et al.
Publicado: (2021)

TP53 gain-of-function mutation modulates the immunosuppressive microenvironment in non-HPV-associated oral squamous cell carcinoma
por: Shi, Yewen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9b2taetu515kbdo6ua61cuosu7