Cargando…

Perioperative Adverse Outcome and Its Predictors After Emergency Laparotomy Among Sigmoid Volvulus Patients: Retrospective Follow-Up Study

BACKGROUND: Acute sigmoid volvulus is a surgical emergency with closed-loop obstruction of the colon that often requires emergency laparotomy, which is associated with a multitude of post-operative complications. Although sigmoid volvulus is the main cause of intestinal obstruction in Ethiopia, loca...

Descripción completa

Detalles Bibliográficos
Autores principales: Deresse, Tilahun, Tesfahun, Esubalew, Gebreegziabher, Zenebe Abebe, Bogale, Mandante, Alemayehu, Dawit, Dessalegn, Megbar, Kifleyohans, Tewodros, Eskandar, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591608/
https://www.ncbi.nlm.nih.gov/pubmed/37876607
http://dx.doi.org/10.2147/OAEM.S430193
_version_ 1785124258817507328
author Deresse, Tilahun
Tesfahun, Esubalew
Gebreegziabher, Zenebe Abebe
Bogale, Mandante
Alemayehu, Dawit
Dessalegn, Megbar
Kifleyohans, Tewodros
Eskandar, George
author_facet Deresse, Tilahun
Tesfahun, Esubalew
Gebreegziabher, Zenebe Abebe
Bogale, Mandante
Alemayehu, Dawit
Dessalegn, Megbar
Kifleyohans, Tewodros
Eskandar, George
author_sort Deresse, Tilahun
collection PubMed
description BACKGROUND: Acute sigmoid volvulus is a surgical emergency with closed-loop obstruction of the colon that often requires emergency laparotomy, which is associated with a multitude of post-operative complications. Although sigmoid volvulus is the main cause of intestinal obstruction in Ethiopia, local studies of its management outcomes are limited. OBJECTIVE: To assess the magnitude and predictors of adverse perioperative outcomes of emergency laparotomy for acute sigmoid volvulus in the Debre Markos Comprehensive Specialized Hospital (DMCSH), Amhara region, Ethiopia in 2023. METHODS: This was a retrospective follow-up study. Descriptive statistics were used to measure perioperative outcomes and other study variables. Bivariable and multivariable logistic regression models were used to identify the predictors of adverse surgical outcomes. Associations were considered significant at p < 0.05 (95% confidence interval). RESULTS: In total, 170 study participants were enrolled, with a response rate of 91.4%. Forty-nine patients (28.8%) developed perioperative adverse outcomes. Pneumonia (29 patients, 28.1%), surgical site infection (19 patients, 18.4%), and wound dehiscence (10 patients, 9.7%) were the most common complications. Pre-operative shock [AOR: 3.87 (95% CI: (1.22, 12.28))], pus or fecal matter contamination of the peritoneum [AOR: 4.43 (95% CI: (1.35, 14.47)], and a higher American Society of Anesthesiologists (ASA) score [AOR: 2.37 (95% CI: (1.05, 5.34))] were identified as predictors of perioperative adverse events. CONCLUSION: The perioperative adverse outcomes in this study were higher than those reported in Ethiopian national and global reports following emergency laparotomies. Hypotension at presentation, pus and/or fecal matter contamination of the peritoneum, and higher ASA scores are strong predictors of increased perioperative adverse outcomes. Therefore, healthcare providers and institutions involved in the delivery of emergency surgical care should emphasize the importance of early surgical intervention, adequate resuscitation, and patient monitoring to improve perioperative outcomes.
format Online
Article
Text
id pubmed-10591608
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-105916082023-10-24 Perioperative Adverse Outcome and Its Predictors After Emergency Laparotomy Among Sigmoid Volvulus Patients: Retrospective Follow-Up Study Deresse, Tilahun Tesfahun, Esubalew Gebreegziabher, Zenebe Abebe Bogale, Mandante Alemayehu, Dawit Dessalegn, Megbar Kifleyohans, Tewodros Eskandar, George Open Access Emerg Med Original Research BACKGROUND: Acute sigmoid volvulus is a surgical emergency with closed-loop obstruction of the colon that often requires emergency laparotomy, which is associated with a multitude of post-operative complications. Although sigmoid volvulus is the main cause of intestinal obstruction in Ethiopia, local studies of its management outcomes are limited. OBJECTIVE: To assess the magnitude and predictors of adverse perioperative outcomes of emergency laparotomy for acute sigmoid volvulus in the Debre Markos Comprehensive Specialized Hospital (DMCSH), Amhara region, Ethiopia in 2023. METHODS: This was a retrospective follow-up study. Descriptive statistics were used to measure perioperative outcomes and other study variables. Bivariable and multivariable logistic regression models were used to identify the predictors of adverse surgical outcomes. Associations were considered significant at p < 0.05 (95% confidence interval). RESULTS: In total, 170 study participants were enrolled, with a response rate of 91.4%. Forty-nine patients (28.8%) developed perioperative adverse outcomes. Pneumonia (29 patients, 28.1%), surgical site infection (19 patients, 18.4%), and wound dehiscence (10 patients, 9.7%) were the most common complications. Pre-operative shock [AOR: 3.87 (95% CI: (1.22, 12.28))], pus or fecal matter contamination of the peritoneum [AOR: 4.43 (95% CI: (1.35, 14.47)], and a higher American Society of Anesthesiologists (ASA) score [AOR: 2.37 (95% CI: (1.05, 5.34))] were identified as predictors of perioperative adverse events. CONCLUSION: The perioperative adverse outcomes in this study were higher than those reported in Ethiopian national and global reports following emergency laparotomies. Hypotension at presentation, pus and/or fecal matter contamination of the peritoneum, and higher ASA scores are strong predictors of increased perioperative adverse outcomes. Therefore, healthcare providers and institutions involved in the delivery of emergency surgical care should emphasize the importance of early surgical intervention, adequate resuscitation, and patient monitoring to improve perioperative outcomes. Dove 2023-10-19 /pmc/articles/PMC10591608/ /pubmed/37876607 http://dx.doi.org/10.2147/OAEM.S430193 Text en © 2023 Deresse et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Deresse, Tilahun
Tesfahun, Esubalew
Gebreegziabher, Zenebe Abebe
Bogale, Mandante
Alemayehu, Dawit
Dessalegn, Megbar
Kifleyohans, Tewodros
Eskandar, George
Perioperative Adverse Outcome and Its Predictors After Emergency Laparotomy Among Sigmoid Volvulus Patients: Retrospective Follow-Up Study
title Perioperative Adverse Outcome and Its Predictors After Emergency Laparotomy Among Sigmoid Volvulus Patients: Retrospective Follow-Up Study
title_full Perioperative Adverse Outcome and Its Predictors After Emergency Laparotomy Among Sigmoid Volvulus Patients: Retrospective Follow-Up Study
title_fullStr Perioperative Adverse Outcome and Its Predictors After Emergency Laparotomy Among Sigmoid Volvulus Patients: Retrospective Follow-Up Study
title_full_unstemmed Perioperative Adverse Outcome and Its Predictors After Emergency Laparotomy Among Sigmoid Volvulus Patients: Retrospective Follow-Up Study
title_short Perioperative Adverse Outcome and Its Predictors After Emergency Laparotomy Among Sigmoid Volvulus Patients: Retrospective Follow-Up Study
title_sort perioperative adverse outcome and its predictors after emergency laparotomy among sigmoid volvulus patients: retrospective follow-up study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591608/
https://www.ncbi.nlm.nih.gov/pubmed/37876607
http://dx.doi.org/10.2147/OAEM.S430193
work_keys_str_mv AT deressetilahun perioperativeadverseoutcomeanditspredictorsafteremergencylaparotomyamongsigmoidvolvuluspatientsretrospectivefollowupstudy
AT tesfahunesubalew perioperativeadverseoutcomeanditspredictorsafteremergencylaparotomyamongsigmoidvolvuluspatientsretrospectivefollowupstudy
AT gebreegziabherzenebeabebe perioperativeadverseoutcomeanditspredictorsafteremergencylaparotomyamongsigmoidvolvuluspatientsretrospectivefollowupstudy
AT bogalemandante perioperativeadverseoutcomeanditspredictorsafteremergencylaparotomyamongsigmoidvolvuluspatientsretrospectivefollowupstudy
AT alemayehudawit perioperativeadverseoutcomeanditspredictorsafteremergencylaparotomyamongsigmoidvolvuluspatientsretrospectivefollowupstudy
AT dessalegnmegbar perioperativeadverseoutcomeanditspredictorsafteremergencylaparotomyamongsigmoidvolvuluspatientsretrospectivefollowupstudy
AT kifleyohanstewodros perioperativeadverseoutcomeanditspredictorsafteremergencylaparotomyamongsigmoidvolvuluspatientsretrospectivefollowupstudy
AT eskandargeorge perioperativeadverseoutcomeanditspredictorsafteremergencylaparotomyamongsigmoidvolvuluspatientsretrospectivefollowupstudy