Spatial heterogeneity of T cell repertoire across NSCLC tumors, tumor edges, adjacent and distant lung tissues

BACKGROUND: A better understanding of T cells in lung cancer and their distribution across tumor-adjacent lungs and peripheral blood is needed to improve efficacy and minimize toxicity from immunotherapy to lung cancer patients. METHODS: Here, we performed CDR3β TCR sequencing of 136 samples from 20...

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Detalles Bibliográficos
Autores principales: Hu, Qikang, Frank, Meredith L., Gao, Yang, Ji, Liyan, Peng, Muyun, Chen, Chen, Wang, Bin, Hu, Yan, Wu, Zeyu, Li, Jina, Shu, Lu, He, Qiongzhi, Zhang, Yingqian, Xia, Xuefeng, Zhang, Jianjun, Yi, Xin, Reuben, Alexandre, Yu, Fenglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591778/
https://www.ncbi.nlm.nih.gov/pubmed/37876834
http://dx.doi.org/10.1080/2162402X.2023.2233399

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