P069 Assessing the prevalence of anatomical abnormalities amongst patients with sleep disordered breathing and high non-invasive ventilation pressure requirements.

BACKGROUND: Adherence and tolerance of positive airway pressure (PAP) therapy is thought to be lower in individuals with sleep-disordered breathing and high pressure requirements. Patients occasionally have physical anatomical abnormalities that can contribute to these high pressure requirements. These anatomical abnormalities may have reversible contributors, which may reduce pressure requirements and thus improve tolerance of positive airway pressure. METHODS: A retrospective single centre cohort study of patients with sleep-disordered breathing was performed. Inclusion criteria was prescription of non-invasive ventilation with inspiratory pressure IPAP >25 cmH2O between 01/01/2013-01/01/2023. All indications for PAP were included. Patient demographics, indications for PAP, sleep study results and anthropomorphic details were assessed. Primary outcome will be the proportion of patients assessed for anatomical abnormalities of the upper airway. PROGRESS TO DATE: To date, 116 patients with high pressure requirements have been identified and data collection is in progress. INTENDED OUTCOME AND IMPACT: Amongst our local cohort, we aim to describe the proportion, demographic and clinical features of patients with sleep-disordered breathing on bilevel positive airway pressure therapy with high pressure requirements. Ultimately, we hope to use this research to inform decision-making with regards to referral to ENT.