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Regulation of ERK2 activity by dynamic S-acylation

Extracellular signal-regulated kinases (ERK1/2) are key effector proteins of the mitogen-activated protein kinase pathway, choreographing essential processes of cellular physiology. Here, we discover that ERK1/2 are subject to S-acylation, a reversible lipid modification of cysteine residues, at C27...

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Detalles Bibliográficos
Autores principales: Azizi, Saara-Anne, Qiu, Tian, Brookes, Noah E., Dickinson, Bryan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591828/
https://www.ncbi.nlm.nih.gov/pubmed/37715953
http://dx.doi.org/10.1016/j.celrep.2023.113135