A combination of two resistance mechanisms is critical for tick-borne encephalitis virus escape from a broadly neutralizing human antibody

Tick-borne encephalitis virus (TBEV) is a flavivirus that causes human neuroinfections and represents a growing health problem. The human monoclonal antibody T025 targets envelope protein domain III (EDIII) of TBEV and related tick-borne flaviviruses, potently neutralizing TBEV in vitro and in precl...

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Detalles Bibliográficos
Autores principales: Svoboda, Pavel, Haviernik, Jan, Bednar, Petr, Matkovic, Milos, Rincón, Tomás Cervantes, Keeffe, Jennifer, Palus, Martin, Salat, Jiri, Agudelo, Marianna, Nussenzweig, Michel C., Cavalli, Andrea, Robbiani, Davide F., Ruzek, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591882/
https://www.ncbi.nlm.nih.gov/pubmed/37715951
http://dx.doi.org/10.1016/j.celrep.2023.113149

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