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A single-cell level comparison of human inner ear organoids with the human cochlea and vestibular organs
Inner ear disorders are among the most common congenital abnormalities; however, current tissue culture models lack the cell type diversity to study these disorders and normal otic development. Here, we demonstrate the robustness of human pluripotent stem cell-derived inner ear organoids (IEOs) and...
Autores principales: | van der Valk, Wouter H., van Beelen, Edward S.A., Steinhart, Matthew R., Nist-Lund, Carl, Osorio, Daniel, de Groot, John C.M.J, Sun, Liang, van Benthem, Peter Paul G., Koehler, Karl R., Locher, Heiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592453/ https://www.ncbi.nlm.nih.gov/pubmed/37289589 http://dx.doi.org/10.1016/j.celrep.2023.112623 |
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