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Identification of aryl hydrocarbon receptor as a barrier to HIV-1 infection and outgrowth in CD4(+) T cells

The aryl hydrocarbon receptor (AhR) regulates Th17-polarized CD4(+) T cell functions, but its role in HIV-1 replication/outgrowth remains unknown. Genetic (CRISPR-Cas9) and pharmacological inhibition reveal AhR as a barrier to HIV-1 replication in T cell receptor (TCR)-activated CD4(+) T cells in vi...

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Detalles Bibliográficos
Autores principales:	Chatterjee, Debashree, Zhang, Yuwei, Ngassaki-Yoka, Christ-Dominique, Dutilleul, Antoine, Khalfi, Soumia, Hernalsteens, Olivier, Wiche Salinas, Tomas Raul, Dias, Jonathan, Chen, Huicheng, Smail, Yasmine, Goulet, Jean-Philippe, Bell, Brendan, Routy, Jean-Pierre, Lint, Carine Van, Ancuta, Petronela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592455/ https://www.ncbi.nlm.nih.gov/pubmed/37310858 http://dx.doi.org/10.1016/j.celrep.2023.112634

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