Loss of PBAF promotes expansion and effector differentiation of CD8(+) T cells during chronic viral infection and cancer

During chronic viral infection and cancer, it has been established that a subset of progenitor CD8(+) T cells continuously gives rise to terminally exhausted cells and cytotoxic effector cells. Although multiple transcriptional programs governing the bifurcated differentiation trajectories have been...

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Detalles Bibliográficos
Autores principales: Kharel, Arjun, Shen, Jian, Brown, Ryan, Chen, Yao, Nguyen, Christine, Alson, Donia, Bluemn, Theresa, Fan, Jie, Gai, Kexin, Zhang, Bin, Kudek, Matthew, Zhu, Nan, Cui, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592487/
https://www.ncbi.nlm.nih.gov/pubmed/37330910
http://dx.doi.org/10.1016/j.celrep.2023.112649

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