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Joint sequence & chromatin neural networks characterize the differential abilities of Forkhead transcription factors to engage inaccessible chromatin

The DNA-binding activities of transcription factors (TFs) are influenced by both intrinsic sequence preferences and extrinsic interactions with cell-specific chromatin landscapes and other regulatory proteins. Disentangling the roles of these binding determinants remains challenging. For example, th...

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Detalles Bibliográficos
Autores principales: Arora, Sonny, Yang, Jianyu, Akiyama, Tomohiko, James, Daniela Q., Morrissey, Alexis, Blanda, Thomas R., Badjatia, Nitika, Lai, William K.M., Ko, Minoru S.H., Pugh, B. Franklin, Mahony, Shaun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592618/
https://www.ncbi.nlm.nih.gov/pubmed/37873361
http://dx.doi.org/10.1101/2023.10.06.561228

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