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Joint sequence & chromatin neural networks characterize the differential abilities of Forkhead transcription factors to engage inaccessible chromatin
The DNA-binding activities of transcription factors (TFs) are influenced by both intrinsic sequence preferences and extrinsic interactions with cell-specific chromatin landscapes and other regulatory proteins. Disentangling the roles of these binding determinants remains challenging. For example, th...
Autores principales: | Arora, Sonny, Yang, Jianyu, Akiyama, Tomohiko, James, Daniela Q., Morrissey, Alexis, Blanda, Thomas R., Badjatia, Nitika, Lai, William K.M., Ko, Minoru S.H., Pugh, B. Franklin, Mahony, Shaun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592618/ https://www.ncbi.nlm.nih.gov/pubmed/37873361 http://dx.doi.org/10.1101/2023.10.06.561228 |
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