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Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver Identifies Tissue- and Sex-Specific Changes with Implications for Genomic Imprinting

BACKGROUND: Maternal exposure to environmental chemicals can cause adverse health effects in offspring. Mounting evidence supports that these effects are influenced, at least in part, by epigenetic modifications. OBJECTIVE: We examined tissue- and sex-specific changes in DNA methylation (DNAm) assoc...

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Detalles Bibliográficos
Autores principales: Morgan, Rachel K., Wang, Kai, Svoboda, Laurie K., Rygiel, Christine A., Lalancette, Claudia, Cavalcante, Raymond, Bartolomei, Marisa S., Prasasya, Rexxi, Neier, Kari, Perera, Bambarendage P.U., Jones, Tamara R, Colacino, Justin A., Sartor, Maureen A., Dolinoy, Dana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592650/
https://www.ncbi.nlm.nih.gov/pubmed/37873115
http://dx.doi.org/10.1101/2023.09.29.560131

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